Summary

AMB Volume 42, Issue 2, 2026 / Pages 173-181 / https://doi.org/10.59393/amb26420201

Human Monkeypox: Weathering the Storm of an Emerging Global Health Concern

Fadhil Z.J., Al-Aameri D.A., Al-Nuaimi B.N., Hatif S.T., Al-kuraishy H.M., Jabir M.S.

Monkeypox virus (MPXV) is an emerging outbreak transmitted between animals and humans. In 2022, the World Health Organization (WHO) announced MPXV cases in six different regions, and over 120 countries reported confirmed cases of MPX. By the end of August 2024, over 100,000 confirmed cases of MPX and more than 220 deaths due to MPX were reported. Notably, the physical contact, especially in the context of sexual intercourse, is the main route of transmission of MPXV that led to the widespread spread in the human population. This route increases the possibility of emerging outbreaks in many different countries outside the virus’s origin. Prevention measures should be implemented urgently to manage the disease worldwide. In order to gain an understanding of this hazardous infection, this review aims to provide a comprehensive review of MPXV infection.

Keywords: Monkeypox, Monkeypox virus, zoonotic, human-to-human transmission

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